> The seven-day successful perfusion of poor-quality livers now allows for a wide range of strategies, e.g. repair of preexisting injury, cleaning of fat deposits in the liver or even regeneration of partial livers.
But the lobes themselves don't regenerate, so it's not a thing that can be done more than a time or two.
Though, i have always been curious as to why the body only has one liver while having pairs of many other organs...
Perhaps it would be far easier for the donor to regrow the majority of their own liver in their own body than it would be for the recipient, given the immune response and other factors that I would imagine complicate a transplant.
Not sure if one week will do it, but could be very viable when this tech is extended to more than a week.
Major advantage of reusing one's liver is the body would be less likely to reject it, hence relying less on immune suppression medications.
Both the ones I knew were in hospice and not a huge intervention for the six weeks, so not a tone of continuing intervention.
I'd guess that liver failure is maybe defined not as 100% failure, but failure to keep up with daily demand due to an external impairment such as cancer, and that this is just a typical curve of declining function until the body becomes too poisoned to survive.
Anybody with more detailed real bio/medical information?
However this kind of technologies open really a lot of new possibilities regarding organ transplantation, and even auto transplantation as describe at the end of the article.
For head (or other organ) artificial alive-keeping we still don't know enough about how they work - and in case of especially the head we don't have the adequate technology yet to properly reconnect the neurons.
It might be that we can do this sooner than keeping the full head alive though, given that there is way more investment in such research to help people with spinal injuries regain motor control.
Oxygenated, nutrition loaded blood mainly. But I'm sure that misses 8 unsolvable essentials...
Preserving sanity for the severed head is a whole other story.